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C-Type Natriuretic Peptide (1-53), human

CAS No. 141294-77-1

C-Type Natriuretic Peptide (1-53), human( —— )

Catalog No. M30280 CAS No. 141294-77-1

CNP, a member of the natriuretic peptide family, was first identified in porcine brain and later found in other mammals as well as non-mammals. Processing of the CNP precursor gives rise to CNP-22 and its N-terminally elongated form, CNP-53. The CNPs share considerable sequence homology with ANP and BNP within the disulfide loop and exert similar pharmacological actions, although with different relative potencies.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    C-Type Natriuretic Peptide (1-53), human
  • Note
    Research use only, not for human use.
  • Brief Description
    CNP, a member of the natriuretic peptide family, was first identified in porcine brain and later found in other mammals as well as non-mammals. Processing of the CNP precursor gives rise to CNP-22 and its N-terminally elongated form, CNP-53. The CNPs share considerable sequence homology with ANP and BNP within the disulfide loop and exert similar pharmacological actions, although with different relative potencies.
  • Description
    CNP, a member of the natriuretic peptide family, was first identified in porcine brain and later found in other mammals as well as non-mammals. Processing of the CNP precursor gives rise to CNP-22 and its N-terminally elongated form, CNP-53. The CNPs share considerable sequence homology with ANP and BNP within the disulfide loop and exert similar pharmacological actions, although with different relative potencies.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Angiotensin Receptor
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    141294-77-1
  • Formula Weight
    5801.77
  • Molecular Formula
    C251H417N81O71S3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Sequence:{Asp}{Leu}{Arg}{Val}{Asp}{Thr}{Lys}{Ser}{Arg}{Ala}{Ala}{Trp}{Ala}{Arg}{Leu}{Leu}{Gln}{Glu}{His}{Pro}{{Asn}{Ala}{Arg}{Lys}{Tyr}{Lys}{Gly}{Ala}{Asn}{Lys}{Lys}{Gly}{Leu}{Ser}{Lys}{Gly}{Cys}{Phe}{Gly}{Leu}{Lys}{Leu}{Asp}{Arg}{Ile}{Gly}{Ser}{Met}{Ser}{Gly}{Leu}{Gly}{Cys}

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Minamino N, et al. N-terminally extended form of C-type natriuretic peptide (CNP-53) identified in porcine brain. Biochem Biophys Res Commun. 1990 Jul 31;170(2):973-9.
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